{"id":540,"date":"2025-10-09T07:25:08","date_gmt":"2025-10-09T07:25:08","guid":{"rendered":"https:\/\/dermatide.net\/?page_id=540"},"modified":"2026-08-25T04:03:58","modified_gmt":"2026-08-25T04:03:58","slug":"science-evidence","status":"publish","type":"page","link":"https:\/\/dermatide.net\/en-us\/science-evidence\/","title":{"rendered":"Science & Evidence"},"content":{"rendered":"\t\t
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Tracing the Scientific Breakthroughs Behind<\/span> AKNETIDE\u00ae<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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AKNETIDE\u00ae <\/sup>R&D has been grounded over a decade of research from molecular discovery to clinical validation. Below is a snapshot of key scientific and regulatory milestones that demonstrate its journey from lab bench to real-world acne care efficacy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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2014<\/h4>

Inception of AMP<\/h2> <\/div>\n

Inception of antimicrobial peptide discovery from nature and lab development<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t

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2019<\/h4>

Granted the world first ever AMP additive for animal nutrition and health<\/h2> <\/div>\n

Granted the world first-ever antimicrobial peptide zootechnical additive for animal nutrition<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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2023<\/h4>

The cyclopeptide was discovered<\/h2> <\/div>\n

AKNETIDE\u00ae<\/sup>, a novel antimicrobial cyclopeptide\u00a0with potent inhibition against C. acne<\/em> and S. aureus<\/em>,\u00a0was discovered<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t

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2024<\/h4>

First clinical study by SGS<\/h2> <\/div>\n

The first-ever clinical study, with SGS Cosmetic Lab, was completed and demonstrated the significant efficacy of sensible acne level alleviation<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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2025<\/h4>

Multi-MOAs established and a strict hospital clinical study completed<\/h2> <\/div>\n

Mechanism Elucidation<\/b><\/strong>: <\/b><\/strong>Multi-MOAs were established\u00a0and proven\u00a0by a leading cosmetic research institute<\/p>

A double-blinded placebo-controlled Clinical Study in a world-famous\u00a0Dermatology Hospital was conducted.<\/p><\/div> <\/div>\n <\/div>\n\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Scientifically proven and Dermatologist Endorsed evidences behind AKNETIDE\u00ae <\/sup><\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Backed by 10+ years of rigorous consistent research of antimicrobial bioactive peptides, and recently validated by leading independent biochemical laboratories\u00a0and top-tier dermatology hospital, AKNETIDE\u00ae\u00a0harvested myriads of evidences, either of mechanism or of clinical studies, enables it deserving\u00a0a\u00a0worldwide breakthrough anti acne cosmetic ingredient designed for EFFICACY\u00a0without bragging.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t

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Randomized placebo-controlled clinicalstudy with Intertek<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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A split-face, placebo-controlled clinical study demonstrated that AKNETIDER\u00ae<\/b><\/sup><\/strong> delivered compelling anti-acne efficacy at Day-3 and Day-7.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tView Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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SGS Clinical Study<\/h4>\t\t\t\t<\/div>\n\t\t\t\t
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AKNETIDE\u00ae <\/sup>embedded prototype formula demonstrated potent efficacy in significantly alleviating volunteers’ acne conditions from black heads to papules in 7 days.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tView Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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In-vitro Safety Studies<\/h4>\t\t\t\t<\/div>\n\t\t\t\t
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Skin irritation, phototoxicity, eye irritation, sensitization\u00a0to skin were all tested NEGATIVE; \u00a0HaCaT MTT Toxicity data was given.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tView Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Published Studies and Patents<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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To be published shortly…<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\n\t\t\t\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Tracing the Scientific Breakthroughs Behind AKNETIDE\u00ae AKNETIDE\u00ae R&D has been grounded over a decade of research from molecular discovery to clinical validation. Below is a snapshot of key scientific and regulatory milestones that demonstrate its journey from lab bench to real-world acne care efficacy. 2014 Inception of AMP Inception of antimicrobial peptide discovery from nature […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-540","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nScience & Evidence - Dermatide<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/dermatide.net\/en-us\/science-evidence\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Science & Evidence - Dermatide\" \/>\n<meta property=\"og:description\" content=\"Tracing the Scientific Breakthroughs Behind AKNETIDE\u00ae AKNETIDE\u00ae R&D has been grounded over a decade of research from molecular discovery to clinical validation. 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